Chronic thromboembolic pulmonary hypertension: animal models

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Chronic thromboembolic pulmonary hypertension: animal models.

Chronic thromboembolic pulmonary hypertension (CTEPH) is a life-threatening disease due to pulmonary artery obstruction by persistent organised clots related to one or more episodes of acute pulmonary embolism. To date, the pathogenesis of CTEPH remains unexplained. Pulmonary endarterectomy removes obstruction from pulmonary vessels and can cure patients. However, some unreachable distal pulmon...

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Drug Therapy in Patients with Chronic Thromboembolic Pulmonary Hypertension

Background: Chronic Thromboembolic Pulmonary Hypertension (CTEPH) results from the obstruction of predominantly major pulmonary vessels by organized blood clots and is one of the causes of pulmonary hypertension. The disease is still underdiagnosed and the true prevalence is not clear. The objective of this study was to determine the clinical characteristics and current management of patients w...

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Chronic thromboembolic pulmonary hypertension.

Copyright © 2011 Massachusetts Medical Society. Chronic thromboembolic pulmonary hypertension is defined as mean pulmonary-artery pressure greater than 25 mm Hg that persists 6 months after pulmonary embolism is diagnosed. The 2008 World Symposium on Pulmonary Hypertension1 emphasized the importance of chronic thromboembolic pulmonary hypertension, which occurs in 2 to 4% of patients after acut...

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Chronic thromboembolic pulmonary hypertension

1. Schölzel BE, Snijder RJ, Mager JJ, et al. Chronic thromboembolic pulmonary hypertension. Neth Heart J. 2014;22:533–41. 2. Correale M, Montrone D, Lacedonia D, et al. Multiprofessional and intrahospital experience for diagnosis and treatment of pulmonary arterial hypertension. Monaldi Arch Chest Dis. 2012;78:205–9. 3. D’Amato N, Correale M, D’Agostino C. Aortic thrombus and acute pulmonary em...

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Chronic thromboembolic pulmonary hypertension.

Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare but debilitating and life-threatening complication of acute pulmonary embolism. CTEPH results from persistent obstruction of pulmonary arteries and progressive vascular remodelling. Not all patients presenting with CTEPH have a history of clinically overt pulmonary embolism. The diagnostic work-up to detect or rule out CTEPH should...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2013

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.00101612